CAS No: 360-70-3

It increases the muscle mass and body weight . It increases the bone mineral density, improves appetite and the sense of well being in chronic illness. Widely indicated in Chronic illness, Anaemia, Osteoporosis, Chronic Obstructive Pulmonary Disease.

Systematic (IUPAC) name: [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,1
7-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] decanoate

This is one of the first steroids known to man. It was developed and distributed in the U.S. in the early 1960’s and has enjoyed a brilliant nearly half century. It was likely developed to combat wasting diseases where patients were restricted to bed rest or couldn’t exercise to maintain lean mass throughout recovery. It’s also one of the few anabolics that block cortisone receptors, allowing less cortisone to arrive at their destinations within the muscle and connective tissue. This is crucial for bodybuilders and it’s one reason why Deca is so popular.

Nandrolone (19-nortestosterone) is an anabolic steroid that may be present naturally in the human body, albeit in minute quantities of less than 0.4 ng/ml.[citation needed] Nandrolone is most commonly sold commercially as its decanoate ester (Deca-Durabolin) and less commonly as a phenylpropionate ester (Durabolin). Nandrolone decanoate is used in the treatment of osteoporosis in postmenopausal women (though now not recommended) at a dose of 50 mg every three weeks. It is also used for some aplastic anaemias.

Nandrolone use is indirectly detectable in urine tests by testing for the presence of 19-norandrosterone, a metabolite of this molecule. The International Olympic Committee has set a limit of 2 ng per ml of urine as the upper limit, beyond which an athlete is suspected of doping.  

Nandrolone binds to the androgen receptor to a greater degree than testosterone, but due to its inability to act on the muscle in ways unmediated by the receptor, has less overall effect on muscle growth. The drug is also unusual in that unlike most anabolic steroids, it is not broken down into the more reactive DHT by the enzyme 5alpha-reductase, but rather into a less effective product. As such, some of the negative effects associated with most such drugs are somewhat mitigated.

The positive effects of the drug include muscle growth, appetite stimulation and increased red blood cell production and bone density. Clinical studies have shown it to be effective in treating anaemia, osteoporosis and some forms of neoplasia including breast cancer, and also acts as a progestin-based contraceptive. For these reasons, nandrolone received FDA approval in 1983, and while sale is now restricted by the Controlled Substances Act, it remains available by prescription in most countries. In addition to legal production, Nandrolone is also extensively produced and used by athletes and bodybuilders seeking an edge in professional competition.

Because nandrolone is not broken down into DHT, the deleterious effects common to most anabolic steroids on the scalp, skin, and prostate are lessened to a degree. The lack of alkylation on the 17?-carbon drastically reduces the drug's liver toxicity. Estrogenic effects resulting from reaction with aromatase are also mitigated as a result of the drug being a progestin, but effects such as gynaecomastia and reduced libido still occur in larger doses. Other side-effects can include erectile dysfunction and cardiovascular damage, as well as several ailments resulting from the drug's effect of lowering levels of luteinizing hormone through negative feedback.

Steroid use, Dosage and Side effects of Nandrolone Decanoate

Nandrolone Decanoate is the most widespread and most commonlyused injectable steroid.Deca's large popularity can be attributed to its numerous possible applications and, for its mostly positiveresults.

Nandrolone Decanoate causes the muscle cell to store morenitrogen than it releases so that a positive nitrogen balance is achieved. Apositive nitrogen balance is synonymous with muscle growth since the musclecell, in this phase, assimilates (accumulates) a larger amount of pro-tein than usual. 

The highly anabolic effect of Nandrolone Decanoate is linked to a moderately androgenic component, so that a good gain in muscle mass andstrength is obtained. At the same time, most athletes notice considerable waterretention which, no doubt, is not as distinct as that with injectable testosterones but which in high doses can also cause a smooth and watery appearance.

Since Deca also stores more water in the connectivetissues, it can temporarily case or even cure existing pain in joints. This isespecially good for those athletes who complain about pain in the shoulder,elbow, and knee; they can often enjoy pain-free workouts during treatment with Nandrolone Decanoate. Athletes use Deca, depending on their needs, for muscle buildupand in preparation for a competition.

Nandrolone is suitable, even above average, to develop muscle mass since it promotes the protein synthesis and simultaneously leads to water retention.